Answers:
What HPV subtype is associated with laryngeal cancer? How does HPV affect prognosis for laryngeal cancer?
A) 8, better prognosis
B)21, better prognosis
C)16, better prognosis
D) 8, worse prognosis
E) 21, worse prognosis
F) 16, worse prognosis
Arrange subglottic, glottic and suprglottic laryngeal cancer from most to least prevalent in the US.
Glottic>Supraglottic>Subglottic
MC Question:
----cancers have less----and therefore have less tendency for bilateral regional spread relative to----cancer.
A) Glottic; lymphatics; supraglottic
B) Glottic; vasculature; supraglottic
C) Supraglottic; lymphatics; glottic
D) Supraglottic; vasculature; glottic
Free Response Questions:
Most reccurence of laryngeal cancer occurs within what time period post treatment?
Quick Facts:
Hemilaryngectomy: removal of one vertical half of larynx.
Indicated for:
-subglottic extension no more than 1 cm below true cords
-a mobile affected cord
-unilateral involvement
-no cartilage invasion
-no extralaryngeal soft tissue involvement
Supraglottic Laryngectomy: removal of supraglottis.
Indicated for:
-T1/2/3 w/ preepiglottic space involvement only
-vocal cords are mobile
-cartilage not involved
-ant. commissure not involved
-pt has good pulm status
-base of tongue not involved past circumvallate papillae
-apex of pyriform sinus not involved
-FEV1 is >50%
Total Laryngectomy: Complete removal of larynx
-anastomosis proximal stump to opening @ root of neck for permanent stoma.
-Indications are:
-T3/4 not amenable to partial laryngectomy or chemo.
-thyroid/cricoid involvement
-direct invasion of surrounding tissues
-tongue base involved past circumvallate
-salvage therapy failures of chemo/radiation.
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